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CVE-2026-31969

HTSlib is a library for reading and writing bioinformatics file formats.

Published Mar 18, 2026 · updated Jun 17, 2026 · htslib htslib

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. When reading data encoded using the method, an out-by-one error in the function check for a full output buffer could result in a single attacker-controlled byte being written beyond the end of a heap allocation. Exploiting this bug causes a heap buffer overflow. If a user opens a file crafted to exploit this issue, it could lead to the program crashing, or overwriting of data and heap structures in ways not expected by the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

Code

The project this record applies to. Exploit listings stay in References.

Timeline

Detection, updates, and resolution for this record.

  1. Mar 18, 2026 · NIST NVD

    Detected

    HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. When reading data encoded using the method, an out-by-one error in the function check for a full output buffer could result in a single attacker-controlled byte being written beyond the end of a heap allo

  2. Jun 17, 2026 · NIST NVD

    Updated

    HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. When reading data encoded using the method, an out-by-one error in the function check for a full output buffer could result in a single attacker-controlled byte being written beyond the end of a heap allo

Affected

  • cpe htslib/htslibversion unspecified
  • cpe htslib/htslib1.23

Sources

  • CVE.orgVulnerability recordCVE-2026-31969

    Official CVE identifier

    cve.org
  • NIST NVDVulnerability recordCVE-2026-31969

    HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. When reading data encoded using the method, an out-by-one error i

    nvd.nist.gov

References