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Vulnerabilities

Vulnerability · CVE-2025-12921

A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13.

Published Nov 9, 2025 · catalog updated Nov 14, 2025 · OpenClinica Community Edition

Last checked Oct 31, 2026. A connected source was read within the last 7 days.

Check if you run it

No confirmed exploitation is on record for CVE-2025-12921. EPSS is 0.57%. Act only if a listed version of OpenClinica Community Edition is installed.

Gaps on this record

  • No vendor fix or required action is stored. Compare the linked advisory before you change production.

Same product and reporting

Severity
Medium5.3
Known exploitation
Not in CISA/VulnCheck KEV
EPSS
0.57%
Remediation
Advisory link
Affected products
vendor OpenClinica Community Edition 3.2

A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.

Are you affected?

Enter the version you run. The result uses only the ranges stored on this record.

The check returns affected, not affected, or incomplete. It does not guess a version that is missing from the record.

  • vendor OpenClinica Community Edition 3.23.2

How to fix CVE-2025-12921

  • No stored fix

    No vendor fix text is stored. Use the linked advisory before you change production.

  • Version check

    Seen in 3.2

  • Advisory

    Open the cve_org record and follow its fix.

  • Official advisories

What to do

Three questions, each answered from this record only. Confirm the vendor advisory before you patch.

Should you patch?

No confirmed exploitation is on record for CVE-2025-12921. EPSS is 0.57%. Act only if a listed version of OpenClinica Community Edition is installed.

Which versions are affected?

Compare what you have installed with OpenClinica Community Edition 3.2 3.2. Compare the installed version with the linked vendor advisory before you change production.

What should an analyst verify?

No weakness class is stored. EPSS 0.57%. There is no CISA KEV listing. No Exploit-DB or Metasploit reference is linked. Use the source links for the original advisory.

Code

The project this record applies to. Exploit listings stay in References.

Timeline

Detection, updates, and resolution for this record.

  1. Nov 9, 2025 · EUVD

    Detected

    A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor wa

  2. Nov 14, 2025 · EUVD

    Updated

    A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor wa

Sources

  • CVE.orgVulnerability recordCVE-2025-12921

    Official CVE identifier

    cve.org
  • EUVDVulnerability recordEUVD-2025-38721

    A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. I

    euvd.enisa.europa.eu

References

Freshness

Last verified in this catalog Oct 31, 2026. Significant claims (KEV, EPSS, CVSS, affected ranges) come from the source rows above — open the original publisher for the authoritative advisory.

  • CVE.orgOct 25, 2026
  • EUVDOct 25, 2026